I've ran both an HE351cw and a 63/68 as the high pressure turbo over my S480 on my daily driver. The HE spooled better, and towed better in the 1800 to 2200 rpm range. The 363 tows better than the HE351 in the 2400 to 3000 rpm range. Basically, to keep the HE351 happy, I would hit hills at 80+ MPH in overdrive to keep RPM in the sweet spot whereas with the 63, I either hit hills at 90+MPH, or simply click down to 3rd gear because it pulls great at 65 to 70 MPH in 3rd at 2400+ RPM whereas the HE351cw would get hot faster in the 2400+ RPM range.
As far as HP, I'm fuel-limited and HP is so close, I can't tell a difference other than the S363 doesn't fall on it's face at 2800 rpm like the HE351cw. Inter-stage boost is nearly identical and depending on wastegate settings, I can make it go from 25 psi to 35 psi at full power with about 78-80 PSI total.
The HE351 was easier to do a brake-stand burnout because it lit faster, and it came to life earlier. In all reality, I'm surprised how similar they run, just moved the power band up 200 rpm or so.